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A Comprehensive
Cohort (Pilot) Study in Type II Diabetes with High Risk of CAD in China (CCMR-301-CCDC)
The number of diabetes patients around the world has increased from 30
million in 1985 to the current 180 million, and is expected to grow to 366
million in 2025, with 75 percent occurring in developing countries such as India and China . In China, economic prosperity and
changes in diet and lifestyles have resulted in steep increase in prevalence of
overweight, obesity, and diabetes. It has been reported that there are 40
million patients with diabetes mellitus in China and an equal number of pre-diabetics . The incidence of diabetes among those aged 20–74 years has increased
from 0.67% in the early 1980s to 2.5-3.21% in the mid 1990s , 6–7% in 2001–2002, and 8-10%
in 2008 in urban area. Type 2 diabetes mellitus is associated with an increased risk
for both micro-and macrovascular complications, and cardiovascular diseases
(CVD) are the most common causes of death in these patients. In
patients with coronary artery disease, patients with diabetes are
associated with more
severe and diffuse atherosclearotic diseases and higher mortality compared to non-diabetic
patients. Preventing the onset or
the worsening of the cardiovascular diseases is thus one of the most important goals
in managing type II diabetes.
This study is thus designed to survey the outcomes
for patients with type 2 diabetes with established cardiovascular diseases or
type 2 diabetes with high risk of cardiovascular diseases under current
treatment regimens, assess unmet needs, physician behaviors, and gaps and
trends in practice, providing a comprehensive knowledge in current management
of diabetes and its cardiovascular risk factors and complications and insight
on opportunities and strategy for future research and development of improved
therapy.
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